The protagonist of the cartoon is Dexter, an 8 year old boy with an above average intelligence. He is expert in physics and computer science, he managed to build a secret scientific laboratory (Whose parents do not have information), located near his bedroom. Dexter is in constant contrast with his older sister Dee Dee, the female protagonist of the cartoon, which is curious, pestiferous and certainly much less intelligent than the little brother, who always manages to enter the laboratory despite it being protected by passwords and access codes very complicated, as well as numerous security devices (to open the door you need to raise a particular book from the library of Dexter). In certain episodes, Dee Dee is considered the damsel in distress, waiting for someone to save her, mainly Dexter. Dee Dee is tall, thin, long arms and legs, and huge feet, with blonde hair, shoulder-length, tied in two tails, and blue eyes.